Monday, April 30, 2018

History Of Blood Group Invention By Karl Landsteiner



Karl Landsteiner

Two blood group systems were discovered by Karl Landsteiner during early experiments with blood transfusion: the ABO group in 1901and in co-operation with Alexander S. Wiener the Rhesus group in 1937. Development of the Coombs test in 1945, the advent of transfusion medicine, and the understanding of ABO hemolytic disease of the newborn led to discovery of more blood groups, and now 33 human blood group systems are recognized by the International Society of Blood Transfusion (ISBT), and in the 33 blood groups, over 600 blood group antigens have been found;many of these are rare or are mainly found in certain ethnic groups.

Czech serologist Jan Janský is credited with the first classification of blood into the four types (A, B, AB, O) in 1907, which remains in use today. Blood types have been used in forensic science and were formerly used to demonstrate the impossibility of paternity (e.g., a type AB man cannot be the father of a type O infant), but both of these uses are being replaced by genetic fingerprinting, which provides greater certainty.

According to the Austrian Federal Ministry of Health[full citation needed] the original terminology used by Karl Landsteiner in 1901 for the classification is A, B and 0 (zero); the "O" (oh) found in the ABO group system is actually a subsequent variation occurred during the translation process, probably due to the similar shape between the number 0 and the letter O.

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